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Activated integrin VLA-4 localizes to the lamellipodia and mediates T cell migration on VCAM-1
Lymphocyte migration from blood into lymphoid tissues or to sites of inflammation occurs through interactions between cell surface integrins and their ligands expressed on the vascular endothelium and the extracellular matrix. Very Late Antigen-4 (VLA-4, α(4)β(1)) is a key integrin in the effective...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2009
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731303/ https://ncbi.nlm.nih.gov/pubmed/19542447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803388 |
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