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The integrin VLA-4 supports tethering and rolling in flow on VCAM-1

Selectins have previously been shown to tether a flowing leukocyte to a vessel wall and mediate rolling. Here, we report that an intergrin, VLA- 4, can also support tethering and rolling. Blood T lymphocytes and alpha 4 integrin-transfected cells can tether in shear flow, and then roll, through bind...

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Detalles Bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2120426/
https://ncbi.nlm.nih.gov/pubmed/7534768
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