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Combined Low Doses of PPARγ and RXR Ligands Trigger an Intrinsic Apoptotic Pathway in Human Breast Cancer Cells
Ligand activation of peroxisome proliferator-activated receptor (PPAR)γ and retinoid X receptor (RXR) induces antitumor effects in cancer. We evaluated the ability of combined treatment with nanomolar levels of the PPARγ ligand rosiglitazone (BRL) and the RXR ligand 9-cis-retinoic acid (9RA) to prom...
Tallennettuna:
Päätekijät: | , , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
American Society for Investigative Pathology
2009
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731145/ https://ncbi.nlm.nih.gov/pubmed/19644018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.081078 |
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