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Spread of Infection and Lymphocyte Depletion in Mice Depends on Polymerase of Influenza Virus
SC35M is a mouse-adapted variant of the highly pathogenic avian influenza virus SC35. We have previously shown that interspecies adaptation is mediated by mutations in the viral polymerase and that it is paralleled by the acquisition of high pathogenicity for mice. In the present study, we have comp...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Investigative Pathology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731136/ https://ncbi.nlm.nih.gov/pubmed/19700749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090339 |
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