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Acylation-Mediated Membrane Anchoring of Avian Influenza Virus Hemagglutinin Is Essential for Fusion Pore Formation and Virus Infectivity

Attachment of palmitic acid to cysteine residues is a common modification of viral glycoproteins. The influenza virus hemagglutinin (HA) has three conserved cysteine residues at its C terminus serving as acylation sites. To analyze the structural and functional roles of acylation, we have generated...

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Hlavní autoři: Wagner, Ralf, Herwig, Astrid, Azzouz, Nahid, Klenk, Hans Dieter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091681/
https://ncbi.nlm.nih.gov/pubmed/15858028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6449-6458.2005
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