Functional Consequences of Mitochondrial DNA Deletions in Human Skin Fibroblasts : Increased Contractile Strength in Collagen Lattices Is Due to Oxidative Stress-Induced Lysyl Oxidase Activity

Deletions within the mitochondrial DNA (mtDNA) are thought to contribute to extrinsic skin aging. To study the translation of mtDNA deletions into functional and structural changes in the skin, we seeded human skin fibroblasts into collagen gels to generate dermal equivalents. These cells were eithe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Majora, Marc, Wittkampf, Tanja, Schuermann, Bianca, Schneider, Maren, Franke, Susanne, Grether-Beck, Susanne, Wilichowski, Ekkehard, Bernerd, Françoise, Schroeder, Peter, Krutmann, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731121/
https://ncbi.nlm.nih.gov/pubmed/19661442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080832
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados