Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice

BACKGROUND: Lats1 (large tumor suppressor 1) codes for a serine/threonine kinase that plays a role in the progression through mitosis. Genetic studies demonstrated that the loss of LATS1 in mouse, and of its ortholog wts (warts) in Drosophila, is associated with increased cancer incidence. There are...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Siam, Rania, Harada, Ryoko, Cadieux, Chantal, Battat, Robert, Vadnais, Charles, Nepveu, Alain
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2009
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731069/
https://ncbi.nlm.nih.gov/pubmed/19656388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-60
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