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Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice
BACKGROUND: Lats1 (large tumor suppressor 1) codes for a serine/threonine kinase that plays a role in the progression through mitosis. Genetic studies demonstrated that the loss of LATS1 in mouse, and of its ortholog wts (warts) in Drosophila, is associated with increased cancer incidence. There are...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731069/ https://ncbi.nlm.nih.gov/pubmed/19656388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-60 |
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