Differences in virulence and immune response induced in a murine model by isolates of Mycobacterium ulcerans from different geographic areas

Buruli ulcer (BU) is the third most common mycobacterial disease in immunocompetent hosts. BU is caused by Mycobacterium ulcerans, which produces skin ulcers and necrosis at the site of infection. The principal virulence factor of M. ulcerans is a polyketide-derived macrolide named mycolactone, whic...

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Detalhes bibliográficos
Main Authors: Ortiz, R Hurtado, Leon, D Aguilar, Estevez, H Orozco, Martin, A, Herrera, J Luna, Romo, L Flores, Portaels, F, Pando, R Hernandez
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Translational Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730853/
https://ncbi.nlm.nih.gov/pubmed/19604267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.03941.x
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