Heterogeneity of Mycolactones Produced by Clinical Isolates of Mycobacterium ulcerans: Implications for Virulence

Mycobacterium ulcerans is the causative agent of Buruli ulcer, a severe necrotizing skin disease endemic in tropical countries. Clinical evidence suggests that M. ulcerans isolates from Asia, Mexico, and Australia may be less virulent than isolates from Africa. In vivo studies suggest that mycolacto...

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Detalhes bibliográficos
Main Authors: Mve-Obiang, Armand, Lee, Richard E., Portaels, Françoise, Small, P. L. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC145382/
https://ncbi.nlm.nih.gov/pubmed/12540557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.2.774-783.2003
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