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The Inhibitory Potencies of Monoclonal Antibodies to the Macrophage Adhesion Molecule Sialoadhesin Are Greatly Increased Following PEGylation

PEGylation of antibodies is known to increase their half-life in systemic circulation, but nothing is known regarding whether PEGylation can improve the inhibitory potency of antibodies against target receptors. In this paper, we have examined this question using antibodies directed to Sialoadhesin...

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Bibliografski detalji
Glavni autori: Ducreux, Julie, Vanbever, Rita, Crocker, Paul R.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730630/
https://ncbi.nlm.nih.gov/pubmed/18808170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800259z
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