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The Inhibitory Potencies of Monoclonal Antibodies to the Macrophage Adhesion Molecule Sialoadhesin Are Greatly Increased Following PEGylation

PEGylation of antibodies is known to increase their half-life in systemic circulation, but nothing is known regarding whether PEGylation can improve the inhibitory potency of antibodies against target receptors. In this paper, we have examined this question using antibodies directed to Sialoadhesin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ducreux, Julie, Vanbever, Rita, Crocker, Paul R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730630/
https://ncbi.nlm.nih.gov/pubmed/18808170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800259z
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