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Fast Mapping of Short Sequences with Mismatches, Insertions and Deletions Using Index Structures

With few exceptions, current methods for short read mapping make use of simple seed heuristics to speed up the search. Most of the underlying matching models neglect the necessity to allow not only mismatches, but also insertions and deletions. Current evaluations indicate, however, that very differ...

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Detalhes bibliográficos
Main Authors: Hoffmann, Steve, Otto, Christian, Kurtz, Stefan, Sharma, Cynthia M., Khaitovich, Philipp, Vogel, Jörg, Stadler, Peter F., Hackermüller, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730575/
https://ncbi.nlm.nih.gov/pubmed/19750212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000502
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