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Rab5-mediated endocytosis of activin is not required for gene activation or long-range signalling in Xenopus

Morphogen gradients provide positional cues for cell fate specification and tissue patterning during embryonic development. One important aspect of morphogen function, the mechanism by which long-range signalling occurs, is still poorly understood. In Xenopus, members of the TGF-β family such as the...

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Autors principals: Hagemann, Anja I., Xu, Xin, Nentwich, Oliver, Hyvonen, Marko, Smith, James C.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730407/
https://ncbi.nlm.nih.gov/pubmed/19605501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.034124
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