Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development

Connexin 43 knockout (Cx43 KO) mice exhibit conotruncal malformations and coronary artery defects. We observed epicardial blisters in the Cx43 KO hearts that suggest defects in epicardial epithelial-mesenchymal transformation (EMT), a process that generates coronary vascular progenitors. Analysis us...

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Bibliografiske detaljer
Main Authors: Rhee, David Y., Zhao, Xiao-Qing, Francis, Richard J. B., Huang, Guo Ying, Mably, John D., Lo, Cecilia W.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2009
Fag:
Development and Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730372/
https://ncbi.nlm.nih.gov/pubmed/19700622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.032334
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