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Receptor tyrosine phosphatases control tracheal tube geometries through negative regulation of Egfr signaling

The formation of epithelial tubes with defined shapes and sizes is essential for organ development. We describe a unique tracheal tubulogenesis phenotype caused by loss of both Drosophila type III receptor tyrosine phosphatases (RPTPs), Ptp4E and Ptp10D. Ptp4E is the only widely expressed Drosophila...

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Detalles Bibliográficos
Autores principales: Jeon, Mili, Zinn, Kai
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730367/
https://ncbi.nlm.nih.gov/pubmed/19675131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.033597
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