Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport

Electrophilic cyclopentenone prostaglandins (cyPGs), such as 15-deoxy-Δ(12,14)-prostaglandin J(2) (15dPGJ(2)), initiate redox-based cell signaling responses including increased intracellular glutathione (GSH) synthesis. We investigated whether cyPGs facilitated GSH efflux and if members of the ATP-c...

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Bibliographic Details
Main Authors: Brechbuhl, Heather M., Min, Elysia, Kariya, Chirag, Frederick, Barbara, Raben, David, Day, Brian J.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730198/
https://ncbi.nlm.nih.gov/pubmed/19520157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.06.005
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