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Acute Vascular Disruption by 5,6-Dimethylxanthenone-4-Acetic Acid in an Orthotopic Model of Human Head and Neck Cancer

The sustenance of most solid tumors including head and neck cancers (HNCs) is strongly dependent on the presence of a functioning vascular network. In this study, we examined the acute effects of a tumor vascular disrupting agent (VDA), 5,6-dimethylxanthenone-4-acetic acid (DMXAA; ASA404), in an ort...

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Autori principali: Seshadri, Mukund, Toth, Karoly
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730133/
https://ncbi.nlm.nih.gov/pubmed/19701496
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