A Computational Model of FGF-2 Binding and HSPG Regulation Under Flow

A novel convection-diffusion-reaction model is developed to simulate fibroblast growth factor (FGF-2) binding to cell surface receptors (FGFRs) and heparan sulfate proteoglycans (HSPGs) under flow conditions within a cylindrical-shaped vessel or capillary. The model consists of a set of coupled nonl...

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Bibliographic Details
Main Authors: Shen, Wensheng, Zhang, Changjiang, Fannon, Michael, Forsten-Williams, Kimberly, Zhang, Jun
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729807/
https://ncbi.nlm.nih.gov/pubmed/19272950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TBME.2008.2002109
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