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Uracil DNA Glycosylase: Revisiting Substrate-Assisted Catalysis by DNA Phosphate Anions
Uracil DNA glycosylase (UNG) is a powerful DNA repair enzyme that has been shown to stabilize a glycosyl cation reaction intermediate and a related tight binding inhibitor using electrostatic interactions with the +1 and −1, but not the +2, phosphodiester group of the single-stranded DNA substrate A...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729715/ https://ncbi.nlm.nih.gov/pubmed/18652484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800854g |
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