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Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study

Recently, the rs6232 (N221D) and rs6235 (S690T) SNPs in the PCSK1 gene were associated with obesity in a meta-analysis comprising more than 13 000 individuals of European ancestry. Each additional minor allele of rs6232 or rs6235 was associated with a 1.34- or 1.22-fold increase in the risk of obesi...

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Hlavní autoři: Kilpeläinen, Tuomas O., Bingham, Sheila A., Khaw, Kay-Tee, Wareham, Nicholas J., Loos, Ruth J.F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729665/
https://ncbi.nlm.nih.gov/pubmed/19528091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp280
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