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Outgrowth of CD4(low/neg)CD25(int) T cells with suppressor function in CD4(+)CD25(+) T cell cultures upon polyclonal stimulation ex vivo

CD4(+)CD25(+) regulatory T cells play an essential role in controlling autoimmunity and allograft rejection. Several ex vivo activation and expansion protocols have been developed to amplify cell numbers and suppressor function of murine and human Tregs. We demonstrate here that ex vivo activation a...

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Bibliografische gegevens
Hoofdauteurs: Vogtenhuber, Christine, O'Shaughnessy, Matthew J., Vignali, Dario A. A., Blazar, Bruce R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729660/
https://ncbi.nlm.nih.gov/pubmed/19050298
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