Invasion of C. neoformans into human brain microvascular endothelial cells requires protein kinase C-α activation

Pathogenic fungus C. neoformans has a predilection for the central nervous system causing devastating meningoencephalitis. Traversal of C. neoformans across the blood-brain barrier (BBB) is a crucial step in the pathogenesis of C. neoformans. Our previous studies have shown that the CPS1 gene is req...

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Autori principali: Jong, Ambrose, Wu, Chun-Hua, Prasadarao, Nemani V., Kwon-Chung, Kyung J., Chang, Yun C., Ouyang, Yannan, Shackleford, Gregory M., Huang, Sheng-He
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729555/
https://ncbi.nlm.nih.gov/pubmed/18489726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2008.01172.x
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