Protein Kinase C Protects Preconditioned Rabbit Hearts by Increasing Sensitivity of Adenosine A(2b)-Dependent Signaling During Early Reperfusion

Although protein kinase C (PKC) plays a key role in ischemic preconditioning (IPC), the actual mechanism of that protection is unknown. We recently found that protection from IPC requires activation of adenosine receptors during early reperfusion. We, therefore, hypothesized PKC might act to increas...

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Autori principali: Kuno, Atsushi, Critz, Stuart D., Cui, Lin, Solodushko, Victoriya, Yang, Xi-Ming, Krahn, Thomas, Albrecht, Barbara, Philipp, Sebastian, Cohen, Michael V., Downey, James M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729547/
https://ncbi.nlm.nih.gov/pubmed/17632123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.05.016
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