Treg Depletion–enhanced IL-2 Treatment Facilitates Therapy of Established Tumors Using Systemically Delivered Oncolytic Virus

There are several roadblocks that hinder systemic delivery of oncolytic viruses to the sites of metastatic disease. These include the tumor vasculature, which provides a physical barrier to tumor-specific virus extravasation. Although interleukin-2 (IL-2) has been used in antitumor therapy, it is as...

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Detaylı Bibliyografya
Asıl Yazarlar: Kottke, Timothy, Galivo, Feorillo, Wongthida, Phonphimon, Diaz, Rosa Maria, Thompson, Jill, Jevremovic, Dragan, Barber, Glen N, Hall, Geoff, Chester, John, Selby, Peter, Harrington, Kevin, Melcher, Alan, Vile, Richard G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729455/
https://ncbi.nlm.nih.gov/pubmed/18431359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.83
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