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p53 mutations as fingerprints for aristolochic acid - an environmental carcinogen in endemic (Balkan) nephropathy

The activation of protooncogenes and inactivation of tumor suppressor genes are considered to be the main molecular events in the multistep process of carcinogenesis. Mutations of the TP53 tumor suppressor gene have been found in nearly all tumor types and are estimated to contribute to more than 50...

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Autori principali: Slade, Neda, Moll, Ute, Brdar, Branko, Zorić, Arijana, Jelaković, Bojan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729401/
https://ncbi.nlm.nih.gov/pubmed/19428366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.01.005
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