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The transcriptional foundation of pluripotency

A fundamental goal in biology is to understand the molecular basis of cell identity. Pluripotent embryonic stem (ES) cell identity is governed by a set of transcription factors centred on the triumvirate of Oct4, Sox2 and Nanog. These proteins often bind to closely localised genomic sites. Recent st...

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Bibliografske podrobnosti
Main Authors: Chambers, Ian, Tomlinson, Simon R.
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729344/
https://ncbi.nlm.nih.gov/pubmed/19542351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.024398
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