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Hedgehog-stimulated stem cells depend on non-canonical activity of the Notch co-activator Mastermind
Normal self-renewal of follicle stem cells (FSCs) in the Drosophila ovary requires Hedgehog (Hh) signaling. Excess Hh signaling, induced by loss of patched (ptc), causes cell-autonomous duplication of FSCs. We have used a genetic screen to identify Mastermind (Mam), the Notch pathway transcriptional...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729338/ https://ncbi.nlm.nih.gov/pubmed/19474148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.035329 |
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