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Directed neuronal differentiation of human embryonic stem cells

BACKGROUND: We have developed a culture system for the efficient and directed differentiation of human embryonic stem cells (HESCs) to neural precursors and neurons. HESC were maintained by manual passaging and were differentiated to a morphologically distinct OCT-4(+)/SSEA-4(- )monolayer cell type...

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Detalhes bibliográficos
Main Authors: Schulz, Thomas C, Palmarini, Gail M, Noggle, Scott A, Weiler, Deborah A, Mitalipova, Maisam M, Condie, Brian G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC272931/
https://ncbi.nlm.nih.gov/pubmed/14572319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-4-27
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