Directed Differentiation of Human Embryonic Stem Cells Toward Placode‐Derived Spiral Ganglion‐Like Sensory Neurons

The ability to generate spiral ganglion neurons (SGNs) from stem cells is a necessary prerequisite for development of cell‐replacement therapies for sensorineural hearing loss. We present a protocol that directs human embryonic stem cells (hESCs) toward a purified population of otic neuronal progeni...

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Vydáno v:Stem Cells Transl Med
Hlavní autoři: Matsuoka, Akihiro J., Morrissey, Zachery D., Zhang, Chaoying, Homma, Kazuaki, Belmadani, Abdelhak, Miller, Charles A., Chadly, Duncan M., Kobayashi, Shun, Edelbrock, Alexandra N., Tanaka‐Matakatsu, Miho, Whitlon, Donna S., Lyass, Ljuba, McGuire, Tammy L., Stupp, Samuel I., Kessler, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Translational Research Articles and Reviews
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442760/
https://ncbi.nlm.nih.gov/pubmed/28186679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.16-0032
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