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High-Content Analysis of Cancer Genome DNA Alterations

New technologies as well as concerted brute-force approaches have increased the content (number of genes) that can be characterized for genomic DNA alterations. Recent advances include the detection of activating point mutations in key kinase genes (BRAF, EGFR, PIK3CA) in multiple cancer types; prel...

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Detalhes bibliográficos
Main Authors: Degenhardt, Yan Y., Wooster, Richard, McCombie, Richard W., Lucito, Robert, Powers, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729060/
https://ncbi.nlm.nih.gov/pubmed/18339543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2008.01.005
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