A role for the TGFβ-Par6 polarity pathway in breast cancer progression

The role of polarity signaling in cancer metastasis is ill defined. Using two three-dimensional culture models of mammary epithelial cells and an orthotopic mouse model of breast cancer, we reveal that Par6 signaling, which is regulated directly by TGFβ, plays a role in breast cancer metastasis. Int...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Viloria-Petit, Alicia M., David, Laurent, Jia, Jun Yong, Erdemir, Tuba, Bane, Anita L., Pinnaduwage, Dushanthi, Roncari, Luba, Narimatsu, Masahiro, Bose, Rohit, Moffat, Jason, Wong, John W., Kerbel, Robert S., O'Malley, Frances P., Andrulis, Irene L., Wrana, Jeffrey L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729014/
https://ncbi.nlm.nih.gov/pubmed/19667198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906796106
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