Loading...

Mutation Accumulation, Soft Selection and the Middle-Class Neighborhood

The “middle-class neighborhood” is a breeding design intended to allow new mutations to accumulate by lessening the effects of purifying selection through the elimination of among-line fitness variation. We show that this design effectively applies soft selection to the experimental population, pote...

Full description

Saved in:
Bibliographic Details
Main Authors: Moorad, Jacob A., Hall, David W.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728876/
https://ncbi.nlm.nih.gov/pubmed/19448272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.101436
Tags: Add Tag
No Tags, Be the first to tag this record!