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Mutation Accumulation, Soft Selection and the Middle-Class Neighborhood
The “middle-class neighborhood” is a breeding design intended to allow new mutations to accumulate by lessening the effects of purifying selection through the elimination of among-line fitness variation. We show that this design effectively applies soft selection to the experimental population, pote...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Genetics Society of America
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728876/ https://ncbi.nlm.nih.gov/pubmed/19448272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.101436 |
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