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Mutation Accumulation, Soft Selection and the Middle-Class Neighborhood

The “middle-class neighborhood” is a breeding design intended to allow new mutations to accumulate by lessening the effects of purifying selection through the elimination of among-line fitness variation. We show that this design effectively applies soft selection to the experimental population, pote...

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Detalhes bibliográficos
Main Authors: Moorad, Jacob A., Hall, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728876/
https://ncbi.nlm.nih.gov/pubmed/19448272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.101436
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