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Inhibition of StearoylCoA Desaturase-1 Inactivates Acetyl-CoA Carboxylase and Impairs Proliferation in Cancer Cells: Role of AMPK

Cancer cells activate the biosynthesis of saturated fatty acids (SFA) and monounsaturated fatty acids (MUFA) in order to sustain an increasing demand for phospholipids with appropriate acyl composition during cell replication. We have previously shown that a stable knockdown of stearoyl-CoA desatura...

詳細記述

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書誌詳細
主要な著者: Scaglia, Natalia, Chisholm, Jeffrey W., Igal, R. Ariel
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728543/
https://ncbi.nlm.nih.gov/pubmed/19710915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006812
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