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Binding to Gating Transduction in Nicotinic Receptors: Cys-Loop Energetically Couples to Pre-M1 and M2–M3 Regions
The nicotinic acetylcholine receptor (AChR) transduces binding of nerve-released ACh into opening of an intrinsic ion channel, yet the intraprotein interactions behind transduction remain to be fully elucidated. Attention has focused on the region of the AChR in which the β1–β2 and Cys-loops from th...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Society for Neuroscience
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728446/ https://ncbi.nlm.nih.gov/pubmed/19279256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6185-08.2009 |
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