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Self-organization of keratin intermediate filaments into cross-linked networks

Keratins, the largest subgroup of intermediate filament (IF) proteins, form a network of 10-nm filaments built from type I/II heterodimers in epithelial cells. A major function of keratin IFs is to protect epithelial cells from mechanical stress. Like filamentous actin, keratin IFs must be cross-lin...

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Autori principali: Lee, Chang-Hun, Coulombe, Pierre A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728393/
https://ncbi.nlm.nih.gov/pubmed/19651890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200810196
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