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IGF-1 Receptor Inhibitors in Clinical Trials—Early Lessons
The insulin-like growth factor pathway plays a major role in cancer cell proliferation, survival and resistance to anti-cancer therapies in many human malignancies, including breast cancer. As a key signaling component of IGF system, the IGF-1 receptor is the target of several investigational agents...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728362/ https://ncbi.nlm.nih.gov/pubmed/19023648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-008-9104-6 |
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