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IGF-1 Receptor Inhibitors in Clinical Trials—Early Lessons

The insulin-like growth factor pathway plays a major role in cancer cell proliferation, survival and resistance to anti-cancer therapies in many human malignancies, including breast cancer. As a key signaling component of IGF system, the IGF-1 receptor is the target of several investigational agents...

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Detalhes bibliográficos
Main Authors: Weroha, S. John, Haluska, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728362/
https://ncbi.nlm.nih.gov/pubmed/19023648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-008-9104-6
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