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Bub1 and Bub3 promote the conversion from monopolar to bipolar chromosome attachment independently of shugoshin

The eukaryotic spindle assembly checkpoint (SAC) delays anaphase in the presence of chromosome attachment errors. Bub3 has been reported to be required for SAC activity in all eukaryotes examined so far. We find that Bub3, unlike its binding partner Bub1, is not essential for the SAC in fission yeas...

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Hlavní autoři: Windecker, Hanna, Langegger, Maria, Heinrich, Stephanie, Hauf, Silke
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728212/
https://ncbi.nlm.nih.gov/pubmed/19680287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.183
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