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Post-Transcriptional Regulation of Chemokine Receptor CXCR4 by Estrogen in HER2 Overexpressing, Estrogen Receptor-Positive Breast Cancer Cells

Expression of the chemokine receptor CXCR4, a G protein-coupled receptor, and HER2, a receptor tyrosine kinase, strongly correlates with the aggressive and metastatic potential of breast cancer cells. We studied estrogen regulation of CXCR4 in estrogen receptor (ER)-positive MCF-7 breast cancer cell...

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Autors principals: Sengupta, Surojeet, Schiff, Rachel, Katzenellenbogen, Benita S.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728144/
https://ncbi.nlm.nih.gov/pubmed/18807177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-008-0186-z
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