GD3, an Over-Expressed, Tumor-Derived Ganglioside, Mediates the Apoptosis of Activated But Not Resting T cells

We previously elucidated an important role for gangliosides in RCC-mediated T-lymphocyte apoptosis, though the mechanism by which they mediated lymphocyte death remained unclear. Here we demonstrate that when added in purified form, GD3 is internalized by activated T-cells, initiating a series of pr...

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Hlavní autoři: Sa, Gaurisankar, Das, Tanya, Moon, Christina, Hilston, Cynthia M., Rayman, Patricia A., Rini, Brian I., Tannenbaum, Charles S., Finke, James H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728031/
https://ncbi.nlm.nih.gov/pubmed/19276353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3776
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