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Polyamine compound deoxyspergualin inhibits heat shock protein-induced activation of immature dendritic cells

Polyamine compound deoxyspergualin (DSG) is a potent immunosuppressive agent that has been applied clinically for protecting graft rejection and treatment of Wegener's granulomatosis. Though DSG can bind to heat-shock proteins (HSPs) in cells, its mechanism of immunosuppressive action remains u...

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Bibliografiske detaljer
Main Authors: Sugawara, Atsushi, Torigoe, Toshihiko, Tamura, Yasuaki, Kamiguchi, Kenjiro, Nemoto, Kyuichi, Oguro, Hiroshi, Sato, Noriyuki
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727995/
https://ncbi.nlm.nih.gov/pubmed/18686015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-008-0064-y
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