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Selective Deletion of the A1 Adenosine Receptor Abolishes Heart-Rate Slowing Effects of Intravascular Adenosine In Vivo

OBJECTIVE: Intravenous adenosine induces temporary bradycardia. This is due to the activation of extracellular adenosine receptors (ARs). While adenosine can signal through any of four ARs (A1AR, A2AAR, A2BAR, A3AR), previous ex vivo studies implicated the A1AR in the heart-rate slowing effects. Her...

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Sonraí Bibleagrafaíochta
Main Authors: Koeppen, Michael, Eckle, Tobias, Eltzschig, Holger K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727950/
https://ncbi.nlm.nih.gov/pubmed/19707555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006784
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