Bradykinin-induced dilation of human coronary arterioles requires NADPH oxidase-derived reactive oxygen species

OBJECTIVE: Hydrogen peroxide (H(2)O(2)) is an endothelium-derived hyperpolarizing factor in human coronary arterioles (HCAs). H(2)O(2) mediates bradykinin (BK)-induced vasodilation and reduces bioavailability of epoxyeicosatrienoic acids (EETs); however, the cellular and enzymatic source of H(2)O(2)...

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Autores principales: Larsen, Brandon T., Bubolz, Aaron H., Mendoza, Suelhem A., Pritchard, Kirkwood A., Gutterman, David D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727937/
https://ncbi.nlm.nih.gov/pubmed/19213944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.169367
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