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Review of tocilizumab in the treatment of rheumatoid arthritis

Constitutively overproduced in proliferating synovial tissues, interleukin-6 (IL-6) is deeply involved in the pathology of rheumatoid arthritis (RA). Tocilizumab is a humanized anti-human IL-6 receptor antibody that binds to soluble and membrane-bound IL-6 receptor, and at detectable levels in blood...

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Bibliografske podrobnosti
Glavni avtor: Okuda, Yasuaki
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727785/
https://ncbi.nlm.nih.gov/pubmed/19707430
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