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Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol
Akt plays a role in protecting macrophages from apoptosis induced by some oxysterols Previously we observed enhanced degradation of Akt in P388D1 moncocyte/macrophages following treatment with 25-hydroxycholesterol (25-OH) or 7-ketocholesterol (7-KC). In the present report we examine the role of the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727748/ https://ncbi.nlm.nih.gov/pubmed/19464253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.05.004 |
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