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TRAIL gene therapy: From preclinical development to clinical application

Numerous studies have investigated the potential use of TNF-related apoptosis-inducing ligand (TRAIL) as a cancer therapeutic since its discovery in 1995 – because TRAIL is a potent inducer of apoptosis in tumor cells but not in normal cells and tissues. Consequently, a great deal is known about TRA...

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Detalhes bibliográficos
Main Authors: Griffith, Thomas S., Stokes, Brittany, Kucaba, Tamara A., Earel, James K., VanOosten, Rebecca L., Brincks, Erik L., Norian, Lyse A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727705/
https://ncbi.nlm.nih.gov/pubmed/19275567
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