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DNA binding-dependent and -independent functions of the Hand2 transcription factor during mouse embryogenesis
The basic helix-loop-helix (bHLH) transcription factor Hand2 is required for growth and development of the heart, branchial arches and limb buds. To determine whether DNA binding is required for Hand2 to regulate the growth and development of these different embryonic tissues, we generated mutant mi...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727559/ https://ncbi.nlm.nih.gov/pubmed/19211672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.034025 |
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