Primary cilia regulate Shh activity in the control of molar tooth number

Primary cilia mediate Hh signalling and mutations in their protein components affect Hh activity. We show that in mice mutant for a cilia intraflagellar transport (IFT) protein, IFT88/polaris, Shh activity is increased in the toothless diastema mesenchyme of the embryonic jaw primordia. This results...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ohazama, Atsushi, Haycraft, Courtney J., Seppala, Maisa, Blackburn, James, Ghafoor, Sarah, Cobourne, Martyn, Martinelli, David C., Fan, Chen-Ming, Peterkova, Renata, Lesot, Herve, Yoder, Bradley K., Sharpe, Paul T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Company of Biologists 2009
विषय:
Research Reports
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727556/
https://ncbi.nlm.nih.gov/pubmed/19211681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.027979
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