טוען...
Primary cilia regulate Shh activity in the control of molar tooth number
Primary cilia mediate Hh signalling and mutations in their protein components affect Hh activity. We show that in mice mutant for a cilia intraflagellar transport (IFT) protein, IFT88/polaris, Shh activity is increased in the toothless diastema mesenchyme of the embryonic jaw primordia. This results...
שמור ב:
Main Authors: | , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Company of Biologists
2009
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727556/ https://ncbi.nlm.nih.gov/pubmed/19211681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.027979 |
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